San Casciano dei Bagni is a town situated in the Valdichiana, in the province of Siena. Its history is tied to the presence of thermal waters, which caught the attention of the gentry over the centuries. In the course of the 20th century, the thermal baths fell into step with the times thanks to the construction of a spa complex and hotel of excellent quality. The religious sites worth visiting are numerous: the great church of San Leonardo, the principal church of San Casciano, the church of Sant’Antonio, the early Christian church of Santa Maria della Colonna—which was built over the remains of a pagan temple—and the church of San Michele Arcangelo.

Having reached Ponte a Rigo, continue along for a few kilometers before entering Lazio, and then follow along the unpaved road with its panorama over the Paglia river valley, until getting to Proceno. Go down to Ponte Gregoriano, before tackling the last steep ascent toward the church of Santo Sepolcro, stopping point for Acquapendente